Table 1.
Table of subject characteristics. ISH: in-situ hybridization; WB: western blot; F: female; M: male; AOD: age at death; PMI: postmortem interval indicated in hours; Rx<6wk: medication with antipsychotic drugs within 6 weeks of death; A.S.H.D: arteriosclerotic heart disease; CHF: chronic heart failure; NIDD: noninsulin-dependent diabetes; HTN: hypertension; COPD: Chronic obstructive pulmonary disease.
| Comparison subjects | |||||||
|---|---|---|---|---|---|---|---|
| # | Methods | Sex | AOD | PMI | pH | Rx<6wk | Cause of death |
| 1 | WB | F | 86 | 4.7 | 6,5 | NA | Unknown |
| 2 | IS | F | 79 | 3.0 | 6,3 | NA | Cardiopulmonary failure |
| 3 | IS | F | 96 | 3.3 | 6,7 | NA | Cardio respiratory failure |
| 4 | WB/IS | F | 90 | 4.2 | 6,0 | NA | Cardiopulmonary failure |
| 5 | WB | F | 74 | 3.0 | 6,0 | NA | Cardio respiratory failure |
| 6 | WB | F | 88 | 5.1 | 6.4 | NA | COPD/Pneumonia/Arthritis |
| 7 | WB | F | 98 | 1.4 | 6.6 | NA | Myocardial infarction, aortic aneurysm |
| 8 | WB/IS | M | 69 | 4.3 | 6,3 | NA | Cancer of lung |
| 9 | WB | F | 82 | 5.7 | 6.1 | NA | Cardiopulmonary arrest |
| 10 | WB | F | 80 | 4.8 | 6.2 | NA | Sepsis |
| 11 | IS | F | 64 | 19.1 | 6,1 | NA | Pulmonary edema |
| 12 | IS | M | 93 | 19.0 | 6,4 | NA | Congestive heart failure |
| 13 | IS | F | 102 | 7.1 | 6,5 | NA | Acute myocardial infarction |
| 14 | WB/IS | F | 73 | 3.4 | 6,3 | NA | Acute myocardial infarction |
| 15 | IS | F | 79 | 7.7 | 6,5 | NA | Acute myocardial infarction |
| 16 | WB/IS | F | 84 | 18.5 | 6,2 | NA | Myocardial infarction |
| 17 | WB/IS | M | 101 | 4.7 | 6,8 | NA | Coronary Artery Disease |
| 18 | WB | M | 95 | 4.1 | 6.5 | NA | Chronic renal failure, N.I.D.D., HTN |
| 19 | WB | M | 65 | 3.8 | 6.8 | NA | Renal failure, Diabetes-Cirrhosis of liver |
| 20 | WB | F | 89 | 2.3 | 6.7 | NA | Bronchopneumonia, Asthma, COPD |
| 21 | WB | F | 83 | 6.2 | 6.8 | NA | Cardiopulmonary arrest |
| 22 | WB | M | 66 | 7.6 | 6.6 | NA | Cardiac arrest |
| 23 | WB | F | 75 | 6.5 | 6.0 | NA | Cardiopulmonary arrest |
| 24 | WB | M | 69 | 7.4 | 6.7 | NA | Septic shocks |
| 25 | WB | M | 74 | 16.6 | 6.7 | NA | Cardiopulmonary arrest |
| 26 | WB | F | 62 | 7.0 | 6.6 | NA | Acute myocardial infarction |
| 27 | WB | M | 76 | 2.9 | 6.3 | NA | Bronchopneumonia bilateral. Atherosclerotic heart disease |
| 28 | WB | M | 60 | 28.8 | 6.6 | NA | Acute myocardial infarction |
| 29 | WB | M | 64 | 4.2 | 6.4 | NA | Acute myocardial infarction |
| 30 | WB | M | 93 | 4.2 | 6.3 | NA | Acute myocardial infarction |
| 31 | WB | M | 85 | 5.3 | 6.5 | NA | Cancer of bladder w Metastasis |
| 32 | WB | M | 59 | 20.4 | 6.7 | NA | CAD; hypertension, deep venous thrombosis |
| 33 | WB | M | 92 | 20.0 | 6.4 | NA | Arrhythmia |
| Schizophrenia subjects | |||||||
|---|---|---|---|---|---|---|---|
| # | Methods | Sex | AOD | PMI | pH | Rx<6wk | Cause of death |
| 1 | IS | F | 86 | 6.9 | 5,8 | Yes | Respiratory insufficiency, renal failure |
| 2 | IS | F | 84 | 15.6 | 6,2 | no | Unknown |
| 3 | WB | M | 58 | 6.7 | 6,2 | Yes | Cardio pulmonary arrest |
| 4 | WB | M | 52 | 21.2 | 6,3 | No | Cardio respiratory failure |
| 5 | WB/IS | M | 84 | 6.2 | 6,5 | Yes | Cardiopulmonary failure |
| 6 | IS | M | 69 | 4.5 | 6,4 | Yes | Cardic Infarction, renal failure |
| 7 | WB | M | 58 | 13.3 | 6,9 | Yes | Cardio respiratory failure |
| 8 | WB | M | 57 | 13.7 | 6,1 | Yes | Cardio respiratory arrest |
| 9 | IS | F | 65 | 5.8 | 5,9 | Yes | Cardiopulmonary failure |
| 10 | WB | M | 63 | 6.2 | 5,9 | No | Cardiopulmonary failure |
| 11 | WB/IS | F | 69 | 13.7 | 6,2 | Yes | Cardio respiratory failure |
| 12 | WB/IS | M | 87 | 11.2 | 6,5 | No | Cardiopulmonary failure |
| 13 | IS | M | 68 | 5.6 | 6,8 | No | Cardiopulmonary failure |
| 14 | WB | M | 86 | 7.0 | 6.3 | Yes | Cardio pulmonary arrest |
| 15 | WB/IS | F | 79 | 20.4 | 7,1 | Yes | Cardiopulmonary arrest, cancer of pancreas |
| 16 | WB/IS | M | 85 | 5.3 | 6,3 | Yes | Cardiopulmonary arrest |
| 17 | WB/IS | M | 73 | 7.9 | 6,5 | Yes | Cardio respiratory failure |
| 18 | IS | M | 66 | 12.1 | 6,5 | No | Acute cardiac failure |
| 19 | IS | F | 76 | 21.2 | 6,1 | Yes | Cardiogenic shock |
| 20 | IS | M | 97 | 9.3 | 6,5 | No | Cardiopulmonary arrest |
| 21 | WB | M | 86 | 14.1 | 6.7 | Yes | A.S.H.D. |
| 22 | IS | M | 66 | 8.4 | 6,7 | Yes | Cardiopulmonary arrest |
| 23 | IS | F | 82 | 18.8 | 6,6 | No | Cardiopulmonary arrest |
| 24 | WB/IS | F | 79 | 9.9 | 6,8 | No | Cardiac arrest |
| 25 | WB/IS | M | 68 | 17.3 | 6,6 | Yes | Cardiopulmonary arrest |
| 26 | WB | M | 69 | 40.2 | 6.7 | Yes | Acute renal failure |
| 27 | WB | M | 76 | 16.6 | 6.7 | No | CHF, Coronary arterial disease, A.S.H.D. |
| 28 | WB | F | 74 | 7.0 | 6.3 | Yes | Cardiopulmonary arrest |
| 29 | WB | M | 57 | 21.4 | 6.4 | Yes | Small cell cancer of lung |
| 30 | WB | F | 81 | 12.5 | 5.9 | No | Acute myocardial infarction |
| 31 | WB | F | 77 | 9.7 | 6.0 | Yes | Cardiopulmonary arrest |
| 32 | WB | M | 56 | 13.5 | 6.5 | No | Cardiopulmonary arrest |
| 33 | WB | F | 81 | 15.1 | 6.7 | No | Cardiopulmonary arrest |
Comp: 18F/15M 80.2 ±12.5 8.1 ±6.9 6.4 ±0.3
Schz: 12F/21M 73.2±11.2 12.1 ±7.2 6.4 ±0.3