Table 1.

Changes in Expression Levels of Genes in the Classic UPR Pathway

Gene Symbol	p Value (t Test)	Fold Change
ABCE1	1.34 × 10−43	−1.6
AHSA1	3.53 × 10−51	−1.9
ASF1B	1.55 × 10−39	−1.6
BAG1	1.06 × 10−35	1.5
BAG2	6.35 × 10−39	−1.7
BAT5	5.68 × 10−32	1.5
CALR	1.82 × 10−38	1.7
CANX	8.20 × 10−29	1.6
CCT2	1.10 × 10−38	−1.9
CCT6A	3.42 × 10−38	−1.6
CCT8	3.98 × 10−11	1.5
CHAF1A	1.18 × 10−35	−1.9
CLGN	2.49 × 10−12	2.3
COPA	5.77 × 10−27	1.6
CREB3L2	2.91 × 10−41	2.0
CREB3L4	5.12 × 10−33	1.8
DDIT3	5.29 × 10−55	8.2
DERL1	7.26 × 10−35	1.7
DERL2	8.45 × 10−40	2.4
DERL3	4.44 × 10−34	3.9
DNAJA1	4.43 × 10−40	−1.8
DNAJA4	1.48 × 10−10	−1.7
DNAJB1	4.82 × 10−41	−2.5
DNAJB11	4.07 × 10−42	2.8
DNAJB5	6.02 × 10−29	2.1
DNAJB6	4.49 × 10−29	−1.9
DNAJB9	8.45 × 10−37	6.0
DNAJC1	5.22 × 10−38	2.2
DNAJC3	1.47 × 10−37	2.5
DNAJC6	1.41 × 10−14	1.8
DNAJC9	4.59 × 10−35	−1.5
EDEM1	1.10 × 10−42	2.5
EIF2A3	2.18 × 10−25	1.7
ERN1	2.27 × 10−36	2.5
ERP44	1.52 × 10−28	1.7
FKBP5	9.27 × 10−42	−1.7
GDF11	2.21 × 10−15	−1.7
GRPEL1	1.76 × 10−34	−1.7
HERPUD1	4.14 × 10−37	2.8
HSP90AA1	1.03 × 10−37	−1.7
HSP90AB1	2.05 × 10−42	−1.5
HSP90B1	6.04 × 10−33	2.0
HSPA1A	3.27 × 10−33	−3.0
HSPA2	6.62 × 10−21	−2.1
HSPA4	2.14 × 10−37	−1.7
HSPA4L	1.56 × 10−35	−1.5
HSPA8	5.31 × 10−37	−2.3
HSPB1	3.95 × 10−29	−1.5
HSPE1	2.42 × 10−47	−2.0
HSPH1	6.27 × 10−43	−2.5
HYOU1	2.49 × 10−45	3.1
P4HB	3.87 × 10−34	1.8
SCO1	1.03 × 10−28	−1.5
SEC63	6.82 × 10−25	1.7
SELS	3.53 × 10−45	2.8
SERPINH1	3.58 × 10−11	1.5
TIMM8A	1.66 × 10−34	−2.4