Table 2.
A List of SNPs that Are Associated with Hearing Loss with p < 0.01 and Are within 1 Mb from the Index SNP rs870729
SNPa | Distance to rs870729 | p Value | r2caseb | D′caseb | r2controlb | D′controlb | D′ Ratioc |
---|---|---|---|---|---|---|---|
rs2992950 | −853628 | 0.002274 | 0.001 | 0.106 | 0 | 0.014 | 7.57 |
rs17080523 | −849341 | 0.002406 | 0 | 0.092 | 0 | 0.002 | 46.00 |
rs7329467 | −62457 | 6.87E-08 | 0.117 | 0.495 | 0.003 | 0.071 | 6.97 |
rs7984378 | −47459 | 0.003742 | 0.015 | 0.234 | 0.002 | 0.084 | 2.79 |
rs2313475 | −31103 | 0.00413 | 0.056 | 0.257 | 0 | 0.027 | 9.52 |
rs3751385 | −18923 | 1.50E-09 | 0.744 | 0.889 | 0.673 | 0.843 | 1.05 |
rs6490527 | 2550 | 0.006606 | 0.211 | 1 | 0.265 | 1 | 1.00 |
rs7319601 | 56340 | 0.007069 | 0.026 | 0.237 | 0.009 | 0.166 | 1.43 |
rs9509124 | 59891 | 0.005835 | 0.031 | 0.256 | 0.01 | 0.172 | 1.49 |
rs9315439 | 63701 | 0.000129 | 0.051 | 0.235 | 0 | 0.007 | 33.57 |
rs7992230 | 66438 | 0.001725 | 0.081 | 0.663 | 0.036 | 0.5 | 1.33 |
rs1537788 | 82693 | 4.71E-05 | 0.075 | 0.373 | 0.033 | 0.277 | 1.35 |
rs9285110 | 85313 | 9.38E-05 | 0.057 | 0.369 | 0.03 | 0.305 | 1.21 |
rs1547721 | 86181 | 0.004168 | 0.075 | 0.639 | 0.037 | 0.51 | 1.25 |
rs7327522 | 89416 | 0.007661 | 0.035 | 0.261 | 0.001 | 0.048 | 5.44 |
rs4769989 | 93031 | 0.002192 | 0.04 | 0.313 | 0.001 | 0.048 | 6.52 |
rs7323752 | 95958 | 0.002151 | 0.04 | 0.323 | 0.002 | 0.084 | 3.85 |
rs7323769 | 95987 | 0.00054 | 0.043 | 0.409 | 0.008 | 0.202 | 2.02 |
rs1953516 | 99267 | 0.00039 | 0.049 | 0.447 | 0.01 | 0.236 | 1.89 |
rs7337231 | 114739 | 0.002022 | 0.028 | 0.309 | 0.009 | 0.204 | 1.51 |
rs9509167 | 125622 | 0.001591 | 0.016 | 0.215 | 0.008 | 0.173 | 1.24 |
rs12868032 | 128169 | 0.003955 | 0.017 | 0.211 | 0.006 | 0.151 | 1.40 |
rs9550637 | 130648 | 0.007389 | 0.029 | 0.221 | 0.002 | 0.06 | 3.68 |
SNPs selected for constructing long-range haplotypes are marked in bold font.
r2 and D′ measure correlation between each SNP and the index SNP rs870729.
D′ ratio is defined as D′case / D′control.