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Additional CLS Families and Genetic Heterogeneity
(A) Pedigrees of additional CLS families.
(B) The LRP4 locus was excluded in families CL-13 and CL-14 by haplotype analysis.
(C and D) Identification of an LRP4 founder mutation, p.D529N, in three Turkish CLS families (C) and of p.D137N in two families from Egypt (D). Identical haplotypes are shown in red.
