Table 3.
Results from the Pretreatment Using HDP-cP-5F2dUrd Fluorouracil
| Animal ID | Group | IOP Difference from the Fellow Eye (mm Hg) | ERG Amp Difference from the Fellow Eye (μV) | Retinal Detachment | Tractional Retinal Detachment (%) |
|---|---|---|---|---|---|
| R27 | HDP-cP-5-F-2dUrd | 5 | 50 | N | 0 |
| R61 | HDP-cP-5-F-2dUrd | 6 | 35 | Y | 17 |
| R86 | HDP-cP-5-F-2dUrd | 1 | 5 | N | 0 |
| R37 | HDP-cP-5-F-2dUrd | 3 | 40 | N | 0 |
| R77 | 5-Fluorouracil | 3 | 60 | Y | 30 |
| R90 | 5-Fluorouracil | 8 | 110 | Y | 90 |
| R58 | 5-Fluorouracil | 7.3 | 170 | Y | 50 |
| R01 | 5-Fluorouracil | 10.3 | 80 | Y | 15 |
| P | 0.05* | 0.02* | 0.07† | 0.014* |
Amp, amplitude (peak of b-wave to trough of a-wave).
Wilcoxon/Kruskal Wallis rank sum test, one tail.
Fisher's exact test, one-tail.