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. Author manuscript; available in PMC: 2010 May 13.
Published in final edited form as: J Infect Dis. 2005 Oct 12;192(10):1806–1814. doi: 10.1086/497146

Table 1.

Interferon (IFN)–γ responses to bromohydrin pyrophosphate (BrHPP) in whole blood from patients with tuberculosis and their household contacts in Kampala, Uganda, according to HIV-1 serostatus.

Parameter HIV-1 negative (n = 122)
HIV-1 positive (n = 56)
Patients with tuberculosis (n = 37) Household contacts (n = 85) Patients with tuberculosis (n = 36) Household contacts (n = 20)
Sex, no. (%) male 20 (54) 34 (40) 16 (44) 9 (45)
Age, mean ± SD, years 27.4 ± 9.1 29.8 ± 13.8 33.6 ± 9 32.4 ± 8.2
IFN-γ response, median (interquartile range), pg/mL 423 (101–935) 746 (335–2223) 131 (13–652) 431 (68–1486)
IFN-γ response, log-transformed mean ± SD, pg/mL 2.49 ± 0.85 2.86 ± 0.78 1.88 ± 1.16 2.23 ± 1.19
Tuberculin skin test response, no. (%) positive ND 63 (74) ND 7 (35)

NOTE. IFN-γ (pg/mL) was measured in supernatants of whole blood stimulated for 7 days with BrHPP and interleukin-2. ND, not determined; TST, tuberculin skin test.