Table 3.
Chemotherapy and Acute Radiotherapy Toxicity
| Arm 1: 75.25 Gy/35 fx (n=8) | Arm 2: 74 Gy/37 fx (n=9) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Grade | Grade | |||||||||
| Category | 1 | 2 | 3 | 4 | 5 | 1 | 2 | 3 | 4 | 5 |
| Allergy/immunology | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
| Blood/bone marrow | 0 | 2 | 4 | 0 | 0 | 3 | 0 | 5 | 0 | 0 |
| Cardiovascular (arrhythmia) | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Cardiovascular (general) | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 0 |
| Coagulation | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Constitutional symptoms | 0 | 2 | 0 | 0 | 0 | 1 | 3 | 1 | 0 | 0 |
| Dermatology/skin | 2 | 1 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 0 |
| Gastrointestinal | 2 | 2 | 1 | 0 | 0 | 2 | 3 | 2 | 0 | 0 |
| Hemorrhage | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| Hepatic | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Infection/febrile neutropenia | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
| Metabolic/laboratory | 1 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| Musculoskeletal | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Neurology | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3 | 0 | 0 |
| Pain | 0 | 2 | 0 | 1 | 0 | 1 | 0 | 2 | 0 | 0 |
| Pulmonary | 0 | 1 | 3 | 0 | 0 | 1 | 2 | 1 | 0 | 0 |
| Renal/genitourinary | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| Worst non-hematologic | 1 (13%) | 1 (13%) | 4 (50%) | 1 (13%) | 1 (13%) | 0 (0%) | 3 (33%) | 5 (56%) | 1 (11%) | 0 (0%) |
| Worst overall | 1 (13%) | 1 (13%) | 4 (50%) | 1 (13%) | 1 (13%) | 0 (0%) | 1 (11%) | 7 (78%) | 1 (11%) | 0 (0%) |