Table 3.

Genes of oxidative stress, mitochondrial electron transport and hypoxia differentially regulated by intermittent hypoxia and sustained hypoxia (4% O₂) compared with normoxia

		IH		SH-4%
Probe ID	Gene Name	Fold Change	q, %	Fold Change	q, %
Genes upregulated by intermittent and sustained hypoxia
GI_4504436-S	Heme oxygenase (decycling) 1 (HO1)	3.18	<0.10	2.76	<0.10
GI_27754195-S	NAD(P)H quinone oxidoreductase 3 (NQO3)	3.16	<0.10	3.27	<0.10
GI_27754205-S	Cytochrome-c oxidase II (MTCO2)	3.01	<0.10	3.00	<0.10
GI_27754207-S	ATP synthase 6 (MTATP6)	2.55	<0.10	2.49	<0.10
GI_20149575-S	Nuclear factor (erythroid-derived 2)-like 2 (NRF2)	2.31	<0.10	1.65	<0.10
GI_27754203-S	Cytochrome-c oxidase I (MTCO1)	2.20	0.289	2.61	<0.10
GI_25014098-S	Selenoprotein K (SELK)	2.16	<0.10	2.24	<0.10
GI_27754201-S	NAD(P)H quinone oxidoreductase 2 (NQO2)	2.02	0.693	2.7	0.178
GI_27754199-S	NAD(P)H quinone oxidoreductase 1 (NQO1)	1.98	0.162	2.11	<0.10
Genes upregulated by intermittent hypoxia only
GI_33519429-A	Thioredoxin reductase 1 (TXNRD1), transcript variant 4	1.96	1.656	NS
GI_42741647-S	15 kDa selenoprotein (SEP15), transcript variant 1	1.77	<0.10	NS
GI_34222132-S	Thioredoxin domain containing (TXNDC)	1.76	0.693	NS
GI_21614497-S	von Hippel-Lindau binding protein 1 (VBP1)	1.61	1.656	NS
Genes upregulated by sustained hypoxia only
GI_19924300-S	Vascular endothelial growth factor C (VEGFC)	NS		1.57	0.384