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. 2010 May 11;102(10):1511–1518. doi: 10.1038/sj.bjc.6605666

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Copyright © 2010 Cancer Research UK

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Time-course kinetics of DNA repair-deficient LCLs. γH2AX foci per nucleus are shown for controls (n=11; open bars), homozygous ATM mutant (three experimental replicates; grey bars) and ligase IV knock-out (three experimental replicates; black bars) human cell lines. γH2AX foci number was counted in cells before (0 h) and 1 and 8 h after exposure to 2 Gy of IR. Error bars represent s.e.m. of γH2AX foci number per nucleus.