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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2010 Apr;69(4):356–371. doi: 10.1097/NEN.0b013e3181d53d98

Figure 6.

Figure 6

Phosphorylated Y31 (pY31) paxillin in control and Alzheimer disease (AD) hippocampi. (A) pY31 paxillin is located in pyramidal neurons in control and AD hippocampi but with no nuclear staining in AD (a, b). pY31 paxillin is localized in Hirano bodies (HB) (c) and plaques (d). (B) Confocal microscopy for pY31 paxillin (green), nuclei (blue) and AT8- labeled phosphorylated Tau (pTau) (red). pY31 paxillin is colocalized in AT8+ pyramidal neurons in both neurofibrillary tangles and neuritic processes in AD (a–f). Scale bars: A, B = 50 µm.