Table 1.

The effects of chrysin in human and rat cell lines. Each study is denoted by the last name of the first author [5,7–10].

Study	Cell type(s)	Concentration use	Title of study
Parajuli et al. 2009	U87-MG, U251, MDA-MB-231 and PC3 cells	40–100 μM	In vitro anti-tumor mechanisms of various Scutellaria extracts and constituent flavonoids.
Izuta et al. 2008	SH-SY5Y cells	≤20 μM	Protective effects of Chinese propolis and its component, chrysin, against neuronal cell death via inhibition of mitochondrial-dependent apoptosis pathway in SH-SY5Y cells.
Weng et al. 2005	Rat C6 glioma cells	10–50 μM	Chrysin induces G1 phase cell cycle arrest in C6 glioma cells through inducing p21Waf1/Cip1 expression and involvement of p38 mitogen-activated protein kinase.
Woo et al. 2004	U937 promonocytic cells	≤10 μM	Chrysin-induced apoptosis is mediated through caspase activation and Akt inactivation in U937 leukemia cells.
Zhang et al. 2004	HeLa cells	≤30 μM	Chrysin and its phosphate ester inhibit cell proliferation and induce apoptosis in Hela cells.