Figure 2. LYN expression is associated with unfavorable outcome.
(A) LYN immunostaining on tissue microarray. Shown are representative breast cancer cases negative (arrow identifies region with tumor cells) or positive for expression of the LYN tyrosine kinase in tumor cells. Note, LYN is expressed in stromal cells in some breast cancer cases (also see Fig. S7). (B) LYN expression in tumor cells predicts unfavorable outcome. Kaplan-Meier analysis comparing LYN positive and negative cases, for relapse-free survival (above) and overall survival (below); P-values shown.