Table 1.
Correct (%) | Accuracy (%) | Omissions (%) | Premature responses | Correct latency (s) | Reward latency (s) | |
---|---|---|---|---|---|---|
75% DMSO | 58.9±3.1 | 63.9±2.5 | 7.7±3.5 | 18.0±3.7 | 0.67±0.04 | 1.43±0.17 |
SalvA | 64.0±2.4 | 66.6±2.0 | 4.1±1.3 | 14.0±1.9 | 0.73±0.02 | 1.51±0.15 |
Saline | 61.0±3.1 | 64.4±2.8 | 5.4±2.1 | 27.2±7.7 | 0.62±0.03 | 1.43±0.04 |
Ketamine | 62.4±4.0 | 66.7±3.2 | 6.9±2.3 | 23.1±5.5 | 0.66±0.04 | 1.34±0.03* |
SalvA (1.0 mg/kg), ketamine (5.0 mg/kg), or vehicle was administered 10 min prior to testing on the short DS version of the 5CSRTT. The discriminative stimulus duration was reduced from the standard 1.0 to 0.5 s for this version of the task.
P<0.05 compared to respective vehicle