Table 2.
Effects of salvA and ketamine on long ITI version of the 5CSRTT
Correct (%) | Accuracy (%) | Omissions (%) | Premature responses | Correct latency (s) | Reward latency (s) | |
---|---|---|---|---|---|---|
75% DMSO | 68.8±3.3 | 72.0±3.0 | 4.6±1.1 | 33.8±6.0 | 0.65±0.04 | 1.36±0.08 |
SalvA | 65.0±4.2 | 74.5±3.4 | 11.7±5.7 | 36.0±7.5 | 0.77±0.08 | 1.51±0.11 |
Saline | 67.2±3.4 | 74.9±2.3 | 10.2±3.9 | 55.6±13.5 | 0.68±0.05 | 1.47±0.06 |
Ketamine | 69.2±2.5 | 71.8±2.2 | 3.8±1.0 | 54.9±10.3 | 0.68±0.04 | 1.38±0.04 |
SalvA (1.0 mg/kg), ketamine (5.0 mg/kg), or vehicle was administered 10 min prior to testing on the long ITI version of the 5CSRTT. The ITI was increased from the standard 5.0 to 9.0 s for this version of the task.