Figure 6. Evidence that Muc2^−/− mice do not have intrinsic defects in anti-microbial activity at their mucosal surface.

A. Quantitative PCR analysis of cnlp (encodes mCRAMP) and inos expression in the cecum and rectal tissues of WT and Muc2^−/− mice. Results represent the means from 3 independent infections, each with 2–3 animals per group. Error bars  =  SEM. B. Titration curve from a microtitre assay showing crude mucin isolated from colorectal tissues of WT mice contains dose-dependent growth activity on C. rodentium. Assay was performed in duplicate for each dilution. Error bars  =  SEM. Results are representative of 2 independent experiments.