Table 1. Frequencies of chromosomal and telomeric abnormalities in wild-type and Ogg1−/− bone marrow cells and primary MEFs.
| Cell types | Fragments & breaks | End-to-end fusion | SFEs |
| Bone Marrow | |||
| Wild type | 0% (0/1919 | 0% (0/1919) | 0.4% (7/1919) |
| Ogg1−/− | 0% (0/1980) | 0% (0/1980) | 0.7% (14/1980) |
| Primary MEFs ( 3% O2 ) | |||
| Wild type | 0% (0/1087) | 0% (0/1087) | 3.2% (35/1087) |
| Ogg1−/− | 0% (0/1140) | 0% (0/1140) | 4.1% (47/1140) |
| Primary MEFs (20% O2) | |||
| Wild type | 0.1% (1/846) | 0% (0/846) | 4.5% (38/846) |
| Ogg1−/− | 0.7% (7/946) | 0.11% (1/946) | 8.4% (79/946)* |
| Primary MEFs (0.5 µ M paraquat) | |||
| Wild type | 0.1% (1/993) | 0.1% (1/993) | 4.1% (41/993) |
| Ogg1−/− | 0% (0/983) | 0.2% (2/983) | 18.6% (183/983)* |
Abnormal events/total chromosomes were shown in parentheses. SFEs: telomere signal free ends. The data were obtained from metaphase spreads and Q-FISH analysis of different mice (n = 6) or MEF lineages (n = 6) of each genotype. * P-value between wild type and Ogg1−/− yielded a statistical difference in indicated categories.