Table 4.

Multivariable marginal logistic regression models determining risk of elevated depressed mood in patients and controls

	Patients			Controls
	aOR	95% CI	P	aOR	95% CI	P
Caregiving × Time interaction
No caregiving
T1	1.00			1.00
T2	0.50	0.29–0.86	0.0119	0.95	0.57–1.57	0.8349
T3	0.59	0.33–1.05	0.0724	0.87	0.53–1.44	0.5972
Caregiving to a child or another person
T1	1.00			1.00
T2	1.14	0.49–2.65	0.7641	1.07	0.51–2.24	0.8659
T3	0.58	0.24–1.42	0.2319	1.04	0.50–2.20	0.9120
Caregiving to both
T1	1.00			1.00
T2	7.20	1.17–44.46	0.0336	0.20	0.02–2.01	0.1700
T3	8.07	0.79–82.20	0.0778	0.12	0.02–0.97	0.0468
Age at diagnosis	0.90	0.87–0.94	<0.0001	0.96	0.94–0.99	0.0104
Social support	0.30	0.22–0.40	<0.0001	0.32	0.25–0.42	<0.0001
Marital status
Married	1.00			1.00
Non-married	0.88	0.54–1.45	0.6246	0.91	0.54–1.55	0.7334
Employment status
Working at least part time	1.00			1.00
Retired	1.18	0.55–2.54	0.6798	1.94	0.97–3.88	0.0610
Unable to work/Unemployed	4.01	2.35–6.84	<0.0001	5.24	2.93–9.36	<0.0001
Homemaker	1.41	0.64–3.14	0.3964	2.61	1.25–5.43	0.0104
Race
White	1.00			1.00
Non-white	1.84	1.03–3.32	0.0408	1.33	0.79–2.22	0.2806
History of depression at baseline	4.24	2.74–6.58	<0.0001	3.19	2.03–5.01	<0.0001
Cancer stage
DCIS	1.00			–	–
I	1.55	0.92–2.59	0.0988	–	–
IIA	1.82	1.02–3.28	0.0444	–	–

aOR adjusted odds ratio, CI confidence interval