Table.
Prevalence of abdominal wall defects in the United Kingdom. Rates are cases per 10 000 total births
| Geographical coverage (reference) | Years | Total No of births | Induced abortions included? | Omphalocele
|
Gastroschisis
|
Ratio of omphalocele to gastroschisis (95% CI) | Both
|
|||
|---|---|---|---|---|---|---|---|---|---|---|
| No | Rate (95% CI) | No | Rate (95% CI) | No | Rate (95% CI) | |||||
| Glasgow (current study) | 1980-93 | 179 067 | Yes | 73 | 4.1 (3.1 to 5.0) | 24 | 1.3 (0.8 to 1.9) | 3.0 (1.9 to 4.8) | 97 | 5.4 (4.3 to 6.5) |
| Northern region4 | 1988-92 | 201 973 | Yes | 43 | 2.1 (1.5 to 2.8) | 56 | 2.8 (2.1 to 3.5) | 0.8 (0.5 to 1.1) | 99 | 4.9 (3.9 to 5.9) |
| Liverpool3 | 1980-8 | 184 530 | Yes | 60 | 3.3 (2.4 to 4.1) | 28 | 1.5 (1.0 to 2.1) | 2.1 (1.4 to 3.4) | 88 | 4.8 (3.8 to 5.8) |
| Belfast3 | 1980-92 | 355 875 | Yes | 105 | 3.0 (2.4 to 3.5) | 29 | 0.8 (0.5 to 1.1) | 3.6 (2.4 to 5.5) | 134 | 3.8 (3.1 to 4.4) |
| χ2=12.2, P=0.007 | χ2=33.5, P<0.001 | χ2=33.6, P<0.0001 | χ2=8.5, P=0.036 | |||||||
| Scotland2 | 1988-95 | 515 759 | No | 63 | 1.2 (0.9 to 1.5) | 97 | 1.9 (1.5 to 2.3) | 0.6 (0.5 to 0.9) | 160 | 3.1 (2.6 to 3.6) |
| England and Wales1* | 1987-93 | 4 859 221 | No | 448 | 0.9 (0.8 to 1.0) | 539 | 1.1 (1.0 to 1.2) | 0.8 (0.7 to 0.9) | 987 | 2.0 (1.9 to 2.2) |
*
Prevalence of all abdominal wall defects ranged from 1.23 per 10 000 births in South West Thames region to 3.11 per 10 000 births in Northern region.