Figure 1.
Hematoxylin/eosin staining of the iliac arteries in the normal group (panel A), high fat diet group (panel B), and high fat diet plus losartan group (panel C). In panel A, the elastic lamina was clear and intact; endothelia and smooth muscle cells (arrow) arranged regularly. In panel B, the elastic lamina was incomplete and neointima was exposed. Numerous smooth muscle cells near the internal elastic lamina arranged irregularly and extended to the intima (arrow). After treatment with losartan as shown in panel C, less neointima was markedly exposed.