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. 2010 May 8;7(2):82–89. doi: 10.7150/ijms.7.82

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Immunohistochemistry for connexin 40 (Cx40) and connexin 43 (Cx43) in the rabbit iliac arteries. Cx40 expression was shown in panel A, B, and C and Cx43 expression in panel D, E, and F. Panel A: Cx40 staining (brown spots, arrow) between the smooth muscle cells in the tunica media of iliac arteries from the normal group. Panel B: Cx40 staining was distributed in both the tunica media and neointima with more prominent staining in the latter. Panel C: After losartan treatment, Cx40 staining was markedly reduced in the neointima of arteries. The distribution of Cx43 was similar to that of Cx40.