TABLE 4.

P values for the association of polymorphisms in candidate genes on chromosome 8 and plasma fatty acid distribution and adiposity-related phenotypes (n = 761)¹

Gene	SNP	TFAs	MUFAs	PUFAs	SFAs	18:1n–7	18:1n−9	18:2n−6	BMI	% Fat	Waist	Triglycerides
ADRB3	rs35361594	0.226	0.267	0.371	0.767	0.304	0.413	0.206	0.025	0.009	0.043	0.545
APOJ	rs10503814	0.173	0.028	0.017	0.619	0.727	0.381	0.037	0.414	0.165	0.799	0.742
	rs11136000	0.604	0.364	0.802	0.382	0.509	0.611	0.368	0.002	0.005	0.003	0.04
	rs1982229	0.992	0.409	0.742	0.916	0.097	0.041	0.388	0.252	0.555	0.126	0.135
	rs538181	0.033	0.076	0.274	0.584	0.197	0.841	0.279	0.161	0.065	0.600	0.784
	rs569205	0.032	0.110	0.263	0.505	0.512	0.910	0.385	0.095	0.022	0.390	0.859
	rs7812347	0.874	0.016	0.722	0.657	0.080	0.024	0.883	0.128	0.032	0.057	0.502
	rs9331891	0.008	0.188	0.057	0.331	0.295	0.218	0.230	0.780	0.688	0.986	0.073
LPL	rs1059611	0.172	0.086	0.828	0.975	0.376	0.994	0.041	0.718	0.517	0.253	6.4 × 10minus6
	rs1121923	0.380	0.199	0.467	0.565	0.863	0.615	0.177	0.024	0.011	0.034	0.636
	rs13702	0.745	0.023	0.558	0.565	0.166	0.501	0.032	0.861	0.575	0.394	6.9 × 10minus5
	rs1534649	0.398	0.144	0.546	0.331	0.807	0.674	0.017	0.605	0.593	0.693	3.3 × 10minus4
	rs17091738	0.041	0.519	0.164	0.493	0.674	0.355	0.154	0.624	0.637	0.607	0.741
	rs1801177	0.041	0.521	0.165	0.494	0.676	0.357	0.271	0.627	0.639	0.609	0.745
	rs248	0.921	0.022	0.033	0.417	0.154	0.145	0.041	0.492	0.962	0.430	0.347
	rs249	0.095	0.130	0.482	0.235	0.822	0.651	0.054	0.652	0.620	0.885	2.8 × 10minus4
	rs255	0.366	0.293	0.558	0.293	0.904	0.668	0.047	0.998	0.918	0.492	0.005
	rs256	0.331	0.272	0.621	0.319	0.932	0.735	0.039	0.967	0.877	0.460	0.003
	rs263	0.522	0.305	0.458	0.157	0.867	0.583	0.055	0.827	0.842	0.645	0.003
	rs285	0.091	0.017	0.395	0.705	0.053	0.374	0.006	0.722	0.664	0.796	0.006
	rs328	0.140	0.076	0.756	0.934	0.357	0.979	0.031	0.749	0.524	0.263	4.5 × 10minus6
	rs3735964	0.141	0.080	0.744	0.912	0.347	0.991	0.026	0.796	0.592	0.315	3.6 × 10minus6
	rs3916027	0.654	0.017	0.394	0.842	0.139	0.476	0.010	0.832	0.496	0.319	9.8 × 10minus5
	rs8176337	0.309	0.087	0.824	0.293	0.984	0.674	0.013	0.740	0.682	0.989	3.4 × 10minus4
MSR1	rs10503573	0.609	0.546	0.509	0.033	0.308	0.780	0.302	0.243	0.080	0.045	0.236
	rs10503574	0.872	0.079	0.049	0.465	0.695	0.028	0.546	0.159	0.141	0.058	0.721
	rs10503575	0.366	0.155	0.311	0.965	0.843	0.304	0.401	0.163	0.038	0.033	0.737
	rs12114599	0.091	0.006	0.011	0.191	0.736	0.021	0.119	0.001	0.004	0.001	0.558
	rs12216764	0.340	0.106	0.922	0.056	0.010	0.702	0.132	0.146	0.089	0.047	0.209
	rs12675698	0.228	0.062	0.044	0.380	0.457	0.232	0.119	0.042	0.026	0.018	0.758
	rs12678503	0.083	0.004	0.010	0.217	0.561	0.014	0.088	0.003	0.009	0.001	0.844
	rs12680619	0.138	0.003	0.007	0.212	0.381	0.009	0.107	0.022	0.038	0.013	0.594
	rs17620929	0.518	0.262	0.754	0.418	0.042	0.471	0.165	0.326	0.320	0.216	0.267
	rs17677191	0.331	0.026	0.017	0.234	0.713	0.122	0.048	0.196	0.240	0.177	0.504
	rs351554	0.310	0.122	0.954	0.067	0.014	0.772	0.127	0.114	0.062	0.041	0.225
	rs918	0.158	0.081	0.056	0.387	0.610	0.276	0.103	0.031	0.035	0.019	0.802
TNFRSF10B	rs1001792	0.676	0.037	0.146	0.676	0.219	0.905	0.190	0.355	0.232	0.287	0.135
	rs10090860	0.845	0.160	0.750	0.467	0.917	0.035	0.443	0.334	0.173	0.193	0.234
	rs10095594	0.815	0.953	0.616	0.818	0.592	0.200	0.498	0.127	0.025	0.130	0.577
	rs1047266	0.727	0.761	0.371	0.298	0.744	0.151	0.031	0.618	0.984	0.593	0.083
	rs10866818	0.012	0.026	0.750	0.233	0.101	0.013	0.989	0.665	0.757	0.646	0.730
	rs1105944	0.006	0.041	0.992	0.164	0.180	0.024	0.701	0.672	0.688	0.602	0.601
	rs12541497	0.026	0.159	0.286	0.155	0.632	0.751	0.214	0.875	0.897	0.280	0.717
	rs12541697	0.003	0.036	0.801	0.086	0.115	0.013	0.371	0.932	0.778	0.849	0.671
	rs35974498	0.989	0.901	0.439	0.411	0.002	0.704	0.755	0.064	0.125	0.557	0.145
	rs4872046	0.155	0.277	0.443	0.824	0.035	0.459	0.804	0.488	0.565	0.649	0.485
	rs6557612	0.071	0.130	0.271	0.456	0.191	0.040	0.717	0.624	9,464	0.774	0.630
	rs7836280	0.606	0.038	0.156	0.693	0.181	0.915	0.194	0.373	0.250	0.324	0.155

¹SOLAR version 4.0 (Southwest Foundation for Biomedical Research, San Antonio, TX) was used to conduct the association analysis (15). MUFAs, monounsaturated fatty acids; PUFAs, polyunsaturated fatty acids; SNP, single nucleotide polymorphism; TFAs, total fatty acids; SFAs, saturated fatty acids. P values <0.05 indicate significance.