Figure 1.

Consensus phylogenetic tree and evidence of p53 family genes, reconstructed from Ensembl database, release 54, and NCBI taxonomy database. Tree branches are proportional to the genome-wide nucleotide substitution rates for jawed vertebrates (euteleostomi), but are qualitative for more primitive species. Evidence for p53 family genes was either extracted from Ensembl database or manually verified using BLAST (for the most recent assemblies available*) (Altschul et al. 1990; Hubbard et al. 2009; Sayers et al. 2009). Evidence for p53 family genes in clams comes from gene isolation by C. Walker and others (Kelley et al. 2001; Cox et al. 2003)