Table 1.
Participants’ Characteristics Measured at the Follow-up Visit at Time of fMRI (n = 30)
Successful Aging Group (n = 10) | Physical Activity Group (n = 20) | p Value of Group Comparison | |
Age, y, M (SD) | 81.45 (2.77) | 80.8 (3.95) | .5 |
Male, n (%) | 3 (30.0) | 5 (25.0) | .4 |
Education, completed high school or equivalent, n (%) | 4 (40.0) | 9 (45.0) | .5 |
Mini-mental score, M (SD) | 27.5 (2.2) | 27.9 (1.8) | .8 |
Self-reported rating of very good health, n (%) | 4 (40) | 8 (40) | .9 |
Brain volume, mm3, M (SD)* | 1296.5 (167.5) | 1350.7 (94.7) | .1 |
Atrophy index (gray matter/CSF volume), M (SD)* | 1.4 (0.1) | 1.4 (0.1) | .9 |
White matter hyperintensities, % of total white matter volume, M (SD)* | 0.35 (0.3) | 0.33 (0.2) | .8 |
DSST during the fMRI task, accuracy, M (SD)† | 66 (0.27) | 82 (0.12) | .02 |
DSST during the fMRI task, response time, ms, M (SD)‡ | 3086.5 (364.8) | 2680.2 (534.7) | .01 |
Notes: CSF = cerebro-spinal fluid; DSST = digit symbol substitution test; fMRI = functional magnetic resonance imaging.
Obtained for n = 18 of 20 in the physical activity intervention group.
Number of correct answer/total number of trial × 100.
Time between stimulus presentation and time of response recording.