Table 5A.
Continued
| Gene tested (Ref.) | SNP tested | Major/ minor alleles (+ strand) | Literature studies
|
TDT results
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of cases: controls | Population | Reported association: P value | Allele | T | Not T | Total | Transmission frequency | TDT χ2 | P value | |||
| SRD5A2 (23) | rs11889731 | T/G | 287:187 | United States (Alabama) | Data not shown | T | 107 | 104 | 211 | 0.507 | 0.04 | 0.836 |
| rs7571644 | A/G | Data not shown | Did not genotype | |||||||||
| rs12470143 | C/T | Data not shown | C | 235 | 227 | 462 | 0.509 | 0.14 | 0.709 | |||
| rs12467911 | C/T | Data not shown | T | 200 | 192 | 392 | 0.510 | 0.16 | 0.686 | |||
| rs2300697 | T/C | Data not shown | Did not genotype | |||||||||
| Haplotype A | T(A)CC(C): 0.003 | TCC | 89.6 | 94.5 | 184.1 | 0.487 | 0.13 | 0.718 | ||||
| rs11675297 | G/A | Data not shown | G | 43 | 32 | 75 | 0.573 | 1.61 | 0.204 | |||
| rs2754530 | C/T | Data not shown | Did not genotype | |||||||||
| rs765138c | G/T | G | 208 | 203 | 411 | 0.506 | 0.06 | 0.805 | ||||
| Haplotype B | GC: 0.019 | GG | 241.1 | 231.8 | 472.9 | 0.510 | 0.18 | 0.669 | ||||
| GT: 0.021 | GT | 229.8 | 227.8 | 457.6 | 0.503 | 0.01 | 0.925 | |||||
| rs523349 | C/G | C:0.015 | C | 183 | 175 | 358 | 0.511 | 0.18 | 0.672 | |||
Minor allele in bold. ns, Not significant.
a
SGTA rs1640262 genotyping failed and was replaced with rs1005556, which is also in intron 1, 590 bp 3′ of rs1640262; rs1005556: G/T.
b
SRD5A1 rs3797179 genotyping assay failed and was replaced with rs6872996, which is also in intron 4 180 bp 3′ of rs3797179; rs6872996: C/T.
c
SRD5A2 rs2754530 genotyping assay failed and was replaced with rs765138, which is also in intron 1 536 bp 3′ of rs2754530; rs765138: G/T.