Skip to main content
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1989 May;86(9):3003–3005. doi: 10.1073/pnas.86.9.3003

Estimating the superiority of a drug to a placebo when all and only those patients at risk are treated with the drug.

H Robbins 1, C H Zhang 1
PMCID: PMC287052  PMID: 2717608

Abstract

It is shown that, under certain assumptions, one can estimate the difference between the effect of a treatment and that of a placebo even when the treatment has been given to all and only those patients who are at risk (as evidenced by a screening examination).

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Robbins H., Zhang C. H. Estimating a treatment effect under biased sampling. Proc Natl Acad Sci U S A. 1988 Jun;85(11):3670–3672. doi: 10.1073/pnas.85.11.3670. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES