Table 5. Hierarchical Regression Models Examining Main Effects and Interactions by Allele Status.
| MEBS Binge Eating | DEBQ Emotional Eating | |||||
|---|---|---|---|---|---|---|
| Models | b | SE | p | b | SE | p |
| Dietary Restraint: | ||||||
| 5-HT2a C allele vs. no C allele | ||||||
| Dietary Restraint | .35 | .01 | <.001 | .25 | .07 | <.001 |
| 5-HT2a C vs. no C | -.06 | .07 | .37 | -.09 | .07 | .20 |
| Dietary Restraint × 5-HT2a | .01 | .01 | .39 | .01 | .01 | .19 |
| 5-HTT s vs. no s allele | ||||||
| Dietary Restraint | .38 | .01 | <.001 | .32 | .06 | <.001 |
| 5-HTT s vs. no s | .09 | .06 | .10 | .03 | .06 | .68 |
| Dietary Restraint × 5-HTT | 0 | .01 | .47 | 0 | .01 | .87 |
| Impulsivity: | ||||||
| 5-HT2a C vs. no C allele | ||||||
| Impulsivity | .21 | .07 | .001 | .20 | .07 | .003 |
| 5-HT2a C vs. no C | -.03 | .07 | .60 | -.07 | .07 | .32 |
| Impulsivity × 5-HT2a | -.05 | .07 | .44 | -.05 | .07 | .43 |
| 5-HTT s vs. no s allele | ||||||
| Impulsivity | .14 | .06 | .03 | .16 | .07 | .01 |
| 5-HTT s vs. no s | .08 | .06 | .17 | 0 | .07 | .99 |
| Impulsivity × 5-HTT | .07 | .06 | .26 | .02 | .07 | .75 |
| Dietary Restraint and Impulsivity: | ||||||
| 5-HT2a C vs. no C allele | ||||||
| Dietary Restraint | .33 | .01 | <.001 | .23 | .07 | .001 |
| Impulsivity | .19 | .06 | .004 | .21 | .07 | .001 |
| 5-HT2a C vs. no C | -.02 | .07 | .74 | -.04 | .07 | .53 |
| Dietary Restraint × 5-HT2a | 0 | .01 | .30 | .01 | .01 | .13 |
| Impulsivity × 5-HT2a | -.08 | .07 | .21 | -.09 | .07 | .17 |
| Dietary Restraint × Impulsivity × 5-HT2a | 0 | 0 | .64 | 0 | 0 | .49 |
| 5-HTT s vs. no s allele | ||||||
| Dietary Restraint | .35 | .06 | <.001 | .30 | .06 | <.001 |
| Impulsivity | .10 | .06 | .10 | .17 | .07 | .01 |
| 5-HTT s vs. no s | .08 | .06 | .17 | 0 | .06 | .95 |
| Dietary Restraint × 5-HTT | 0 | .01 | .54 | 0 | 0 | .81 |
| Impulsivity × 5-HTT | .05 | .06 | .38 | 0 | .07 | .89 |
| Dietary Restraint × Impulsivity × 5-HTT | 0 | .01 | .99 | 0 | 0 | .49 |
Note. MEBS= Minnesota Eating Behaviors Survey; DEBQ= Dutch Eating Behavior Questionnaire; 5-HT= serotonin; 5-HT2a T102C= serotonin-2A receptor gene T102C polymorphism; 5-HTTLPR= serotonin transporter length promoter polymorphism