Skip to main content
. 2010 Mar 10;24(5):930–940. doi: 10.1210/me.2009-0531

Figure 2.

Figure 2

ICI partially rescued decidualization defect of PRCre/+;COUP-TFIIflox/flox mutant mice. A, Experimental scheme of rescue for induced decidualization defect by ICI injection. B–E, Induced decidualization occurred in PRCre/+;COUP-TFIIflox/flox mutant mice treated with ICI. B, Control mice treated with oil 5 d after stimulation by intraluminal oil infusion. The right horn was stimulated, and the left horn was unstimulated. Only the right horn was decidualized. C, Mutant mice treated with oil 5 d after stimulation. No decidualization was observed. D, Control mice treated with ICI 5 d after stimulation by intraluminal oil infusion. The right horn was stimulated, and the left horn was untreated. Only the right horn was decidualized. E, Mutant mice treated with ICI 5 d after stimulation by intraluminal oil infusion. The right horn was stimulated, and the left horn was untreated. Only the right horn was decidualized (scale bar, 10 mm). F, Ratio of right to left horn in weight. Rescue in mutant mice was statistically significant. White bars, control; black bars, mutant (control mice with oil, n = 4; mutant mice with oil, n = 4; control mice with ICI, n = 7; mutant mice with ICI, n = 5; *, P < 0.01; **, P < 0.005). E, E2; eP, E2 + P4; D, decidualized; ND, nondecidualized.