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r/U scales with the diploid population size, N. At the “major” sites, Ns for the corresponding diploid population is 315, as estimated for “major” mutations. At the BGS sites, selection occurs with a constant selection coefficient, so that Ns = 10 for the diploid population. The mutation rates at all sites are also scaled by the population size. L = 32 kb in all cases; each data point is the average of four simulation runs.
