Table 4. Findings of patients seeking care for acute respiratory infections at the Hospital Civil de Guadalajara during the (H1N1) pandemic 2009—Mexico ◊.
All hospitalized patients treated with oseltamivir (N = 233)‡ | All ambulatory patients treated with oseltamivir as outpatients (N = 286) ‡ | All patients treated with oseltamivir with seasonal influenza A cases (N = 42) ∞ | All patients treated with oseltamivir with pandemic (H1N1) 2009 cases (N = 104) ∞ | |
Findings | ||||
Median temperature (°C) | 38.5 | 37.7 | 38.5 | 38 |
Hypoxia N (%) | 9 (5%) | 0 (0%) | 1 (2%) | 1 (1%) |
Lymphopenia | 156 (69%) | 117 (41%) | 27 (64%) | 66 (63%) |
Thrombocytopenia | 35 (15%) | 19 (7%) | 2 (5%) | 9 (9%) |
Radiology N (%) | Of 205 hospitalized patients who had chest X-ray [of which 83 had chest CT] | Of 258 ambulatory patients who had chest X-ray [of which 35 had chest CT] | Of 36 patients who tested positive for seasonal influenza A and who had chest X-ray s[of which 16 had chest CT] | Of 95 patients who tested positive for pandemic (H1N1) and who had chest X-rays [of which 30 had chest CT] |
Abnormal chest X-ray | 79 (39%) | 112 (43%) | 14 (39%) | 59 (62%)¥ |
Abnormal lung CT | 91 (97%) | 30 (86%) | 16 (100%) | 30 (100%) |
Bilateral infiltrates | 49 (53%) | 23 (64%) | 12 (75%) | 28 (93%)* |
Tree-in bud appearance | 69 (73%) | 26 (72%) | 15 (94%) | 28 (93%)* |
Involvement of basal zone | 62 (66%) | 24 (67%) | 16 (100%) | 30 (100%)* |
Air trapping | 52 (55%) | 23 (64%) | 15 (94%) | 27 (90%)* |
Centrilobular nodules | 49 (52%) | 21 (58%) | 13 (81%) | 24 (80%)* |
Thickened interlobar septa | 48 (51%) | 21 (58%) | 12 (75%) | 28 (93%)* |
Multifocal distribution | 38 (40%) | 13 (36%) | 11 (69%) | 19 (63%)* |
Involvement of middle zone | 27 (29%) | 9 (25%) | 6 (37%) | 18 (60%)* |
Segmental consolidation | 15 (16%) | 1 (3%) | 1 (6%) | 5 (17%) |
Segmental distribution | 14 (15%) | 0 (0%) | 1 (6%) | 3 (10%) |
Involvement of apical zone | 10 (11%) | 4 (11%) | 1 (6%) | 3 (10%) |
Peribronchial ground glass | 7 (7%) | 4 (11%) | 1 (6%) | 7 (23%)* |
¥p = 0.01 when comparing patients who tested positive for seasonal influenza A with those who tested positive for pandemic (H1N1) 2009.
*p≤0.009 when comparing patients who tested positive for pandemic (H1N1) 2009 to those who tested negative.
‡Includes all hospitalized cases regardless of influenza RT-PCR test results.
∞Includes all hospitalized cases and ambulatory patients treated with oseltamivir who tested positive for influenza A.
◊Insufficient data available from patients discharged from triage without oseltamivir to include in table.