Table 7. Several indices of desaturases and elongases in plasma of MDD-R patients compared with a matched non-depressed control groupa.
| Controls (n = 65) | Delta (n = 137) | |
| Delta-6 omega-3 (C18∶4n-3/C18∶3n-3) | 0.029±0.039 | 0.023±0.039 |
| Delta-5 omega-3 (C20∶5n-3/C18∶4n-3) | 25.25±17.56 | 26.96±21.6 |
| Delta-6 omega-3 (C22∶6n-3/C22∶5n-3) | 3.99±1.44 | 4.33±1.49 |
| Elongase (C22∶5n-3/C20∶5n-3) | 0.66±0.34 | 0.52±0.25** |
| Delta-6 omega-6 (C18∶3n-6/C18∶2n-6) | 0.016±0.007 | 0.016±0.008 |
| Delta-5 omega-6 (C20∶4n-6/C20∶3n-6) | 3.94±1.22 | 3.95±1.45 |
| Delta 6 omega-6 (C22∶5n-6/C22∶4n-6) | 0.67±0.16 | 0.65±0.22 |
| Elongase (C20∶3n-6/C18∶3n-6) | 3.81±2.67 | 3.47±3.05 |
| Elongase (C22∶4n-6/C20∶4n-6) | 0.025±0.007 | 0.024±0.007 |
| Delta-9 (C14∶1n-5/C14∶0) | 0.052±0.032 | 0.103±0.114*** |
| Delta-9 (C16∶1n-7/C16∶0) | 0.02±0.003 | 0.02±0.02 |
| Delta-9 (C18∶1n-9/C18∶0) | 2.64±0.55 | 3.10±0.77*** |
| Delta-9 (C24∶1n-9/C24∶0) | 1.714±0.485 | 0.529±0.380** |
| Elongase (18∶∶1 n-9/C16∶1 n-9) | 54.20±47.88 | 55.02±64.23 |
| Elongase (C20∶1 n-9/C18∶1n-9) | 0.007±0.002 | 0.007±0.006 |
| Elongase (22∶1 n-9/C20∶1 n-9) | 0.90±0.71 | 0.33±0.61*** |
| Elongase (C24∶1 n-9/C22∶1n-9) | 7.70±6.56 | 13.62±6.90*** |
| Elongase (C18∶1n-7/C16∶1n-7) | 0.77±0.25 | 0.65±0.28** |
| Elongase (C20∶1n-7/C18∶1n-7) | 0.08±0.04 | 0.05±0.10* |
| Elongase (C16∶0/C14∶0) | 20.62±6.26 | 18.26±6.54* |
| Elongase (C18∶0/C16∶0) | 0.28±0.04 | 0.28±0.29 |
| Elongase (C20∶0/C18∶0) | 0.035±0.05 | 0.037±0.009* |
| Elongase (C22∶0/C20∶0) | 2.32±0.36 | 1.97±0.57*** |
| Elongase (C24∶0/C22∶0) | 0.65±0.069 | 0.71±0.12*** |
a
Independent means t-tests: significantly different in comparison to controls at * p<.05, ** p<.01, *** p<.001.