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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Synapse. 2010 Jul;64(7):528–532. doi: 10.1002/syn.20758

Figure 2. Impairment of medial perforant path LTP is reversible by mineralocorticoid receptor activation in diabetic rats.

Figure 2

(A), Experimental design. (B), Preincubation with 30 nM aldosterone, with continued application of aldosterone in the perfusion medium during recording, restored LTP at medial perforant path synapses in the dentate gyrus. (C), There was no effect of pretreatment with 500 nM RU486, a glucocorticoid receptor antagonist.