Table 1.
Differentially expressed proteins identified by MALDI-TOF PMF in the serum of hepatocellular carcinoma and normal healthy controls.
| Spot Number | Protein name | MW (kDa) | pI | Fold change (Ca/N) | P value (t test) |
|---|---|---|---|---|---|
| 1 | S-adenosylmethionine synthetase isoform type-1 | 43.6 | 5.86 | 4.21 | 0.005 |
| 2 | Glycine N-methyltransferase | 32.6 | 6.58 | 4.56 | 0.007 |
| 3 | Haptoglobin precursor | 38.9 | 6.42 | 5.10 | 0.004 |
| 4 | Serum amyloid P-component precursor | 25.4 | 6.10 | 3.84 | 0.018 |
| 5 | Glyceraldehyde-3-phosphate dehydrogenase | 35.9 | 8.58 | 5.73 | 0.003 |
| 6 | Heat shock protein 90 | 83.1 | 4.97 | 7.04 | <0.0001 |
| 7 | Annexin V | 35.8 | 4.98 | 3.89 | 0.012 |
| 8 | Carbonic anhydrase I | 28.9 | 6.59 | −6.73 | 0.002 |
| 9 | Beta-galactoside-binding lectin | 15.1 | 5.34 | −6.09 | <0.0001 |
| 10 | Vitamin D-binding protein | 52.8 | 5.20 | −5.24 | 0.004 |
| 11 | Apolipoprotein A-I | 28.1 | 5.30 | −3.59 | 0.017 |
| 12 | Annexin 4 | 36.1 | 5.80 | −4.32 | 0.006 |