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. Author manuscript; available in PMC: 2010 May 16.
Published in final edited form as: Neurobiol Aging. 2007 Jan 12;29(5):724–738. doi: 10.1016/j.neurobiolaging.2006.12.005

Fig. 5.

Fig. 5

Photomicrographs of transverse sections of adult rat brain showing the distribution of PS1 immunoreactivity and its co-localization with nicastrin in the diagonal band of Broca (A-C), striatum (D-F), cortex (G-J) and hippocampal formation (K-M). Note the widespread distribution of immunoreactive PS1 in various regions of the adult rat brain (A, D, G, H, K). Double labeling experiment showed that PS1 is co-localized with nicastrin in all neurons located in the diagonal band of Broca (B, C), striatum (E, F), cortex (I, J) and hippocampus (L, M) of the adult rat brain. Scale bar = 50 μm. MS, medial septum; DBB, diagonal band complex; Hil, hilus; GrDG, granular cell layer of the dentate gyrus; Py, pyramidal cell layer.