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. 2010 Apr 23;11:203. doi: 10.1186/1471-2105-11-203

Figure 2.

Figure 2

Schematic diagrams of the 4 forms of BS reads, mapping and post processing. 2A. BS reads may be in one of the 4 forms: +FW, +RC, -FW, -RC. 2B. Bowtie aligns C/T converted reads to the C/T converted strands. During the post processing, the number of mismatches is counted except those between read Ts and genomic Cs. Low-quality mappings with many mismatches are removed.