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Model of enzymatic digestion and crystal structures of Aβ. (A) Enzymatic digestion patterns estimated based on the enzymatic specificities. (B) Structure of 5mer of Aβ(1-42) peptides with cross-beta structure. (C) Enlargement of cross-beta structure around K28 in (B). The data of (B) and (C) were obtained from Protein Data Bank (2beg) and processed by Facio 12.1.2 (33).
