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Effect of NOS inhibition on intracellular zinc ion concentrations in PC12 cells. CONTROL: no RSI, no L-NAME treatment; L-NAME: treated with 500 μM L-NAME in complete culture medium for 1 hour; RSI: 1 hour after RSI; and RSI+L-NAME: treated with 500 μM L-NAME immediately after RSI for 1 hour. Data are represented as mean ± SD (n = 3, *p < 0.001 compared to CONTROL, and #p < 0.001 compared to RSI by one-way ANOVA with Bonferroni adjustment for multiple comparisons).
