Table 1.
Author | Stress agent | Patients | Women | Prior CAD |
PET Radiotracer |
Sens | Spec | PPV | NPV | Accuracy |
---|---|---|---|---|---|---|---|---|---|---|
Sampson*98 | Dipyridamole, adenosine, dobutamine |
102 | 0.42 | 0 | 82Rb | 0.93 | 0.83 | 0.80 | 0.94 | 0.87 |
Bateman103 | Dipyridamole | 112 | 0.46 | 0.25 | 82Rb | 0.87 | 0.93 | 0.95 | 0.81 | 0.89 |
Marwick130 | Dipyridamole + Hand grip | 74 | 0.19 | 0.49 | 82Rb | 0.90 | 1 | 1 | 0.36 | 0.91 |
Grover-McKay131 | Dipyridamole + Hand grip | 31 | 0.01 | 0.13 | 82Rb | 1 | 0.73 | 0.80 | 1 | 0.87 |
Stewart57 | Dipyridamole | 81 | 0.36 | 0.42 | 82Rb | 0.83 | 0.86 | 0.94 | 0.64 | 0.84 |
Go127 | Dipyridamole | 202 | NR | 0.47 | 82Rb | 0.93 | 78 | 0.93 | 0.80 | 0.90 |
Demer34 | Dipyridamole | 193 | 0.26 | 0.34 | 82Rb/13NH3 | 83 | 0.95 | 0.98 | 0.60 | 0.85 |
Tamaki99 | Supine Bike | 51 | NR | 0.75 | 13NH3 | 0.98 | 1 | 1 | 0.75 | 0.98 |
Gould33 | Dipyridamole + Hand grip | 31 | NR | NR | 82Rb/13NH3 | 0.95 | 1 | 1 | 0.90 | 0.97 |
Weighted summary | 877 | 0.29 | 0.35 | 0.90 | 0.89 | 0.94 | 0.73 | 0.90 |
Sens, Sensitivity; Spec, specificity; PPV, positive predictive value; NPV, negative predictive value.
Study using PET/CT (where CT is used for attenuation correction only). Adapted with permission from Di Carli MF et al.6