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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Nucl Cardiol. 2010 Jun;17(3):498–513. doi: 10.1007/s12350-010-9223-5

Table 1.

Summary of published literature regarding diagnostic accuracy of PET MPI

Author Stress agent Patients Women Prior
CAD
PET
Radiotracer
Sens Spec PPV NPV Accuracy
Sampson*98 Dipyridamole, adenosine,
 dobutamine
102 0.42 0 82Rb 0.93 0.83 0.80 0.94 0.87
Bateman103 Dipyridamole 112 0.46 0.25 82Rb 0.87 0.93 0.95 0.81 0.89
Marwick130 Dipyridamole + Hand grip 74 0.19 0.49 82Rb 0.90 1 1 0.36 0.91
Grover-McKay131 Dipyridamole + Hand grip 31 0.01 0.13 82Rb 1 0.73 0.80 1 0.87
Stewart57 Dipyridamole 81 0.36 0.42 82Rb 0.83 0.86 0.94 0.64 0.84
Go127 Dipyridamole 202 NR 0.47 82Rb 0.93 78 0.93 0.80 0.90
Demer34 Dipyridamole 193 0.26 0.34 82Rb/13NH3 83 0.95 0.98 0.60 0.85
Tamaki99 Supine Bike 51 NR 0.75 13NH3 0.98 1 1 0.75 0.98
Gould33 Dipyridamole + Hand grip 31 NR NR 82Rb/13NH3 0.95 1 1 0.90 0.97
Weighted summary 877 0.29 0.35 0.90 0.89 0.94 0.73 0.90

Sens, Sensitivity; Spec, specificity; PPV, positive predictive value; NPV, negative predictive value.

*

Study using PET/CT (where CT is used for attenuation correction only). Adapted with permission from Di Carli MF et al.6