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Proteome-wide amino acid frequency distributions. The frequency of occurrence for the penultimate amino acid (i.e. Met-X) residue of protein N termini is given in black solid bars, and for comparison, the frequency of occurrence over all intact proteins present in the proteome is give by the striped bars (data were taken from the Swiss-Prot v56.2 database for H. sapiens (n = 18,821), D. melanogaster (n = 2789), S. cerevisiae (n = 6551), and H. salinarum (n = 443)).
