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. 2010 Mar 17;285(21):16206–16217. doi: 10.1074/jbc.M109.078576

FIGURE 8.

FIGURE 8.

A, immunohistochemical staining of p53 on transverse sections of E9.5 control (CT) and transgenic (TG) littermates (magnification, ×10). B, graphical presentation of p53-positive cells in the sclerotome from serial sections of control and transgenic littermates (n = 3). Error bars, S.D. C, immunofluorescence staining of p53 (green) and COX-2 (red) on transverse sections of E10.5 control and transgenic littermates using confocal microscopy (magnification, ×40). Nuclei were stained with 4′,6-diamidino-2-phenylindole (DAPI) (blue). NT, neural tube. D, higher magnification view of the boxed area in the sclerotome of the transgenic embryo in C.