Skip to main content
. 2010 May 17;2010:289873. doi: 10.1155/2010/289873

Figure 2.

Figure 2

Sequencing results of STAT3 cDNA. (a) Heterozygous mutation in STAT3 genomic sequence of the patient. (b) Schematic of STAT3 amino acid structure and the identified mutation, H437P (1310A → C) in the DNA binding domain. (c) Pedigree of this family affected by the Hyper-IgE syndrome, the mutation was de novo, not inheritance.