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Effect of intrathecal administration of DPCPX on zymosan-induced visceral hyperalgesia. DPCPX, when injected intrathecally 5 minutes before the intrathecal administration of R-PIA, prevents the decrease in VMR to CRD by R-PIA.
DPCPX, 8-cyclopentyl-1,3-dipropylxanthine; R-PIA, R(-)-N6-(2-phenylisopropyl)-adenosine; VMR, visceromotor response; CRD, colorectal distension.
