. Author manuscript; available in PMC: 2011 Mar 1.

Published in final edited form as: Circ Cardiovasc Qual Outcomes. 2010 Jan 19;3(2):159–164. doi: 10.1161/CIRCOUTCOMES.109.875369

Table 2.

Association of Cystatin C with Sudden Cardiac Death

Measure and Outcome Cystatin C and SCD	Tertile 1	Tertile 2	Tertile 3
Cystatin C (mg/liter)	≤ 0.91	0.92–1.09	≥1.10
Cystatin-based eGFR^* (ml/min/1.73m²)	≥86	69–85	≤68
No. of participants	1579	1582	1304
No of SCD events	15	40	36
Hazard Ratio (95% CI)
Unadjusted	1.00	3.13 (1.67, 5.86)	3.92 (2.05, 7.47)
Adjusted^†	1.00	2.72 (1.44, 5.16)	2.67 (1.33, 5.35)

Cystatin based estimated glomerular filtration rate (eGFR) = 76.7 × cystatin C⁻¹.¹⁹

^†

Adjusted for age, gender, race, current smoking, alcohol use, LDL, HDL, diabetes, systolic blood pressure, diastolic blood pressure, calcium channel blockers, diuretics, aspirin, left ventricular hypertrophy, physical activity, family history of cardiovascular disease, and myocardial infarction and congestive heart failure as time dependent covariates