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. Author manuscript; available in PMC: 2010 May 17.
Published in final edited form as: J Cell Physiol. 2009 Feb;218(2):385–393. doi: 10.1002/jcp.21610

FIGURE 6. Kir2.2 and Kir2.3 Are Not Up-regulated by Rac1DN.

FIGURE 6

A&C) Representative current traces from cells transfected with (A) Kir2.2 or (C) Kir2.3 cDNA and either a control plasmid (Ctrl) or dominant-negative Rac1 (Rac1DN) cDNA. Superimposed current traces are shown for 200 ms voltage steps from -120 to -20 mV in 10 mV increments from a holding potential of -60 mV. Scale bars: 50 ms and 250 pA. B&D) Left: Current-voltage relationship of Kir2.2 (B) or Kir2.3 (D) in control (filled squares) and Rac1DN (open squares) transfected cells. Right: Normalized current densities measured in control and Rac1DN transfected cells at –100 mV. Numbers above columns indicate number of cells in each condition. No significance was detected with non-parametric t-tests at <0.05.