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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Bioanal Rev. 2009 Dec;1(1):7–24. doi: 10.1007/s12566-009-0001-2

Table 1.

More than 30 DAACPs have been discovered in the last 38 years.

Source Peptide [Reference] Sequence1 Species
land mollusc Achatina
neuropeptides
Achatin I [11] GdFAD Achatina fulica
Fulicin [43] FdNEFVa Achatina fulica
Fulyal [12] YdAEFLa Achatina fulica
marine mollusc Conus
toxin
Contryphan [14] GCOdWEPWCa Conus radiatus
Des-[Gly 1]contryphan-R [14] COdWEPWCa Conus radiatus
Contryphan-P [16] GCPdWDPWCa Conus purpurascens
Contryphan-Sm [16] GCOdWQPWCa Conus stercusmuscarum
Bromocontryphan-R [15] GCOdWEPW(6-bromo-W)Ca Conus radiatus
Contryphan-R [16] GCOdWEPWCa(disulfide bond) Conus radiatus
Leu-Contryphan-P [17] GCVdLLPWC Conus purpurascens
Leu-contryphan-Tx [120] CVdLYPWCa Conus textile
Contryphan-Tx [120] GCOdWQPYCa Conus textile
R11a (I-superfamily) [19] dF at 44th in 46 a.a. Conus radiatus
R11b,c [18] dF at 44th in 46 a.a.,dL at 42nd in 44 a.a. Conus radiatus
Conomap-Vt [21] AdFVKGSAQRVAHGY Conus vitulinus
Conomarphin (M super family) [22] DWEYHAHPKONSdFWT Conus marmoreus
Conophan [23] AOANSdVWS Conus gladiator
other marine molluscan
peptides
NdWFa [13] NdWFa Aplysia kurodai
Mytilus-FFRF amide [25] AdLAGDHFFRFa Mytilus edulis
Ocp-1/4 [24] GdFGD/GdSWD Octopus minor
crustacean hyperglycemic
hormone
CHHA, cHHB [26] pGlu-VdFDQACK Homarus americanus
Prc CHH-II [27] dF at 3rd in 72 a.a. Procambarus clarkii(crayfish)
spider venom peptide IVB (ω-agatoxin-TK) [28, 121] dS at 46th 46 a.a. Agelenopsis aperta
frog skin toxin Dermorphin [5] YdAFGYPSa Phyllomedusa sauvagei
Deltorphin(met) [6] YdMFHLMDa Phyllomedusa sauvagei
Deltorphin(leu) [7] YdLFADVASTIGDFFHSIa Phyllomedusa burmeisteri
Deltorphin A (Dermenkephalin) [8] YdMFHLMDa Phyllomedusa sauvagei
Deltorphins I (B) II (C) (ala) [9] YdAFD(E)VVGa Phyllomedusa bicolor
Bombinin (H3-H5) [10] D-aIle at 2nd in 21 a.a. Bombina variegata
platypus peptides Platypus peptide (OvCNPb) [29] LdLHDHPNPRKYKPANKKGLSKGCFG
LKLDRIGSTSGLGC
Ornithorhynchus anatinus
DLP-2 [30] dM at 2nd in 42 a.a. Ornithorhynchus anatinus
1

Each amino acid is represented by its one letter abbreviation, the letter following a “d” indicates that amino acid is in D-form, and “a” means amidation of the C-terminal residue.