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Intensity of the Staining with Antibody to Total EGFR versus Mutation Status
| Total EGFR | 0 | 1+ | 2+ | 3+ |
|---|---|---|---|---|
| Wild-type (n = 145) | 86 (59.3%) | 13 (8.9%) | 25 (17.2%) | 21 (14.5%) |
| L858R + (n = 18) | 7 (38.8%) | 2 (11.1%) | 3 (16.6%) | 6 (33.3%) |
| Exon 19 del + (n = 55) | 15 (27.3%) | 4 (7.3%) | 11 (20%) | 25 (45.6%) |
P value for 2 × 2 table defined by staining 0-1+ vs 2-3+ and EGFR wild-type vs either mutant = 0.0002 (Fisher exact test).
