Table 5.

Summary of IHC Results on TMA Cases and Mutation Status Based on PCR-Based Fragment Analysis for EGFR Exon 19 Deletion

	Exon 19 mutation analysis (PCR-based fragment analysis)
	Mutation+	Mutation−	Total
A. 15-bp deletion cases only
IHC+	20	2	22
IHC−	0	161	161
Total	20	163	183
B. Exon 19 deletion cases
IHC+	23	2	25
IHC−	8	161	169
Total	31	163	194

Sensitivity in A is 100% (20/20). Sensitivity in B is 74.2% (23/31). Specificity is 98.8% (161/163), considering true negatives as cases lacking any type of exon 19 deletion.