Figure 1.

Exemplary array CGH plots of pathogenic CNCs. Class 1: a deletion or duplication of a single DNA segment; class 2: a deletion of the terminal region of one chromosome and a duplication of the terminal region of another chromosome; class 3: a deletion in one chromosome and a duplication in another with at least one interstitial alteration; class 4: a deletion and a duplication involving a contiguous genomic region within the same chromosome arm; class 5: a deletion and a duplication on different arms of the same chromosome; and class 6: represents a heterogeneous group of compound imbalances, not included in this figure.