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NiSO4-induced TUNEL staining in adult mouse OE. (A–C) TUNEL staining of DNA fragmentation following instillation of vehicle (0 mg/kg; A) or 2.5 mg/kg NiSO4 at 1 day (B) or 3 days (C) postinstillation. Dashed lines delineate basal lamina. Scale bar = 50 μm. (D) Quantification of TUNEL+ cells in ectoturbinate 2 and endoturbinate II. *p < 0.01, **p < 0.001 versus vehicle control; #p < 0.001 versus 1 day.
