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. 2010 Mar 8;115(2):557–568. doi: 10.1093/toxsci/kfq072

FIG. 2.

FIG. 2.

GFAP-Nrf2 exhibit similar induction of mRNA related to gliosis or immune response. Mice injected with 0.5 μmol malonate were sacrificed 24 h, 48 h, or 7 days after lesioning and mRNA levels were evaluated for (A) GFAP, (B) Iba-1, (C) Mac-1, (D) gp67phox, and (E) gp91phox (n = 3–5 mice per group). No statistically significant genotype effect was found for any gene. Time had a significant effect in all genes except GFAP (p < 0.05). Malonate treatment produced statistically significant effects in all genes. *p < 0.05 compared with vehicle hemisphere by Bonferroni posttest. #p < 0.05 compared with wild-type animals by Bonferroni posttest.