Figure 3.

Apical ES. This illustration depicts several proteins that have been described to exist at the apical ES, namely the cadherin–catenin, nectin–afadin, α6β1 integrin–laminin α3β3γ3 and JAM–Par/CAR multi-protein complexes (see also table 1). The apical ES is unique with hybrid-like characteristics because it is composed of several proteins that are generally found in focal contacts and TJs. For simplicity, only proteins that were discussed in the text are included in this figure.